Brendan Egan
Dr
Contact Details
Associate Professor of Sport and Exercise Physiology
XG05
T:+353 (0) 1 700 8803
F:+353 (0) 1 700 8888
E:brendan.egan@dcu.ie
W:https://www.researchgate.net/profile/Brendan-Egan
Brendan is an Associate Professor of Sport and Exercise Physiology, and currently Head of School for the School of Health and Human Performance at DCU. His current research investigates skeletal muscle function and adaptation across the life course, with special interest in the synergy between nutrition and exercise interventions ranging from athletes to older adults. His research group performs human trials involving both acute and chronic interventions for outcomes around performance (physical and cognitive), recovery and adaptation, and have employed a wide range of experimental designs, and have been complimented by molecular analysis tools include transcriptomics, proteomics and metabolomics. Nutrients recently and presently under investigation include caffeine, creatine, omega-3 fatty acids, resveratrol, leucine, protein hydrolysates, beetroot juice, and exogenous ketones.
Brendan received his BSc Sport and Exercise Science from the University of Limerick in 2003, MSc Sport and Exercise Nutrition from Loughborough University in 2004, and PhD from Dublin City University in 2008, before completing two years of post-doctoral training with Prof. Juleen Zierath’s Integrative Physiology group at the Karolinska Institute, Sweden. His doctoral studies focussed on skeletal muscle adaptation to exercise, and in particular the continuity between acute molecular responses to individual bouts of exercise and adaptations induced by exercise training, whereas his post-doctoral training utilised animal models and in vitro cell systems to investigate the transcriptional regulation of skeletal muscle development and mechanisms of insulin resistance. He joined the faculty in the School of Public Health, Physiotherapy, and Sport Science at University College Dublin in 2011, where he spent five years before moving to DCU. He is also currently a Visiting Research Scientist at the Florida Institute for Human and Machine Cognition, Pensacola, FL USA, and a Principal Investigator at the National Institute for Cellular Biotechnology at DCU.
Outside of academia, through his sporting career as an inter-county Gaelic footballer with Sligo from 2003 to 2017, Brendan has had a lifelong association with sport, training and performance at all levels of competition from grassroots to elite level, and also practices in the field as a performance nutritionist with emphasis on field-based team sports, and endurance athletes.
Peer Reviewed Journal
| Year | Publication | |
|---|---|---|
| 2022 | Waldman, H.S.; Bryant, A.R.; Shepherd, B.D.; Egan, B.; McAllister, M.J. (2022) 'No Effect of a Ketone Monoester on Markers of Stress and Performance in a Live-Burn Search and Rescue in Firefighters'. Journal of Strength and Conditioning Research, 36 . [Link] [DOI] | |
| 2023 | Nolan, D.; Elliott-Sale, K.J.; Egan, B. (2023) 'Prevalence of hormonal contraceptive use and reported side effects of the menstrual cycle and hormonal contraceptive use in powerlifting and rugby'. Physician and Sportsmedicine, 51 . [Link] [DOI] | |
| 2023 | Timmons, J.F.; Beatty, A.; Stout, C.; Ivory, A.; Carroll, C.; Egan, B. (2023) 'Increased Lean Body Mass After Bodyweight-Based High Intensity Interval Training in Overweight and Obese Men'. Research Quarterly for Exercise and Sport, 94 . [Link] [DOI] | |
| 2022 | Murphy, C.H.; Connolly, C.; Flanagan, E.M.; Mitchelson, K.A.J.; de Marco Castro, E.; Egan, B.; Brennan, L.; Roche, H.M. (2022) 'Interindividual variability in response to protein and fish oil supplementation in older adults: a randomized controlled trial'. Journal of Cachexia, Sarcopenia and Muscle, 13 . [Link] [DOI] | |
| 2021 | Murphy, C.H.; Flanagan, E.M.; De Vito, G.; Susta, D.; Mitchelson, K.A.J.; De Marco Castro, E.; Senden, J.M.G.; Goessens, J.P.B.; Mik?osz, A.; Chabowski, A.; Segurado, R.; Corish, C.A.; Mccarthy, S.N.; Egan, B.; Van Loon, L.J.C.; Roche, H.M. (2021) 'Does supplementation with leucine-enriched protein alone and in combination with fish-oil-derived n-3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? A randomized, double-blind, placebo-controlled trial'. American Journal of Clinical Nutrition, 113 . [Link] [DOI] | |
| 2021 | Timmons, J.F.; Hone, M.; Cogan, K.E.; Duffy, O.; Egan, B. (2021) 'Increased Leg Strength After Concurrent Aerobic and Resistance Exercise Training in Older Adults Is Augmented by a Whole Food-Based High Protein Diet Intervention'. Frontiers In Sports And Active Living, 3 . [Link] [DOI] | |
| 2020 | Connor, J; Egan, B (2020) 'Comparison of hot water immersion at self-adjusted maximum tolerable temperature, with or without the addition of salt, for rapid weight loss in mixed martial arts athletes'. Biology of Sport, 38 (1). [DOI] | |
| 2020 | McSwiney, FT; Fusco, B; McCabe, L; Lombard, A; Crowley, P; Walsh, J; Hone, M; Egan, B (2020) 'Changes in body composition and substrate utilization after a short-term ketogenic diet in endurance-trained males'. Biology of Sport, 38 (1). [DOI] | |
| 2022 | Scotto di Palumbo, A.; McSwiney, F.T.; Hone, M.; McMorrow, A.M.; Lynch, G.; De Vito, G.; Egan, B. (2022) 'Effects of a Long Chain n-3 Polyunsaturated Fatty Acid-rich Multi-ingredient Nutrition Supplement on Body Composition and Physical Function in Older Adults with Low Skeletal Muscle Mass'. Journal of Dietary Supplements, 19 . [Link] [DOI] | |
| 2021 | Brady, A.J.; Langton, H.M.; Mulligan, M.; Egan, B. (2021) 'Effects of 8 wk of 16:8 Time-restricted Eating in Male Middle- and Long-Distance Runners'. Medicine and Science in Sports and Exercise, 53 . [Link] [DOI] | |
| 2021 | Lees, M.J.; Nolan, D.; Amigo-Benavent, M.; Raleigh, C.J.; Khatib, N.; Harnedy-Rothwell, P.; Fitzgerald, R.J.; Egan, B.; Carson, B.P. (2021) 'A fish-derived protein hydrolysate induces postprandial aminoacidaemia and skeletal muscle anabolism in an in vitro cell model using ex vivo human serum'. Nutrients, 13 . [Link] [DOI] | |
| 2021 | Hone, M; Timmons, JF; Egan, B (2021) 'Increases in protein intake, protein distribution score, and micronutrient intakes in older adults in response to a whole food-based dietary intervention'. Aging clinical and experimental research, 34 (4). [DOI] | |
| 2020 | Reynolds, CME; Egan, B; O' Malley, EG; Kennedy, RAK; Sheehan, SR; Turner, MJ (2020) 'A longitudinal, observational study of women who persisted in smoking in successive pregnancies'. Journal of Public Health, 42 :18-26. [DOI] | |
| 2019 | Hone, M; Nugent, AP; Walton, J; McNulty, BA; Egan, B (2019) 'Habitual protein intake, protein distribution patterns and dietary sources in Irish adults with stratification by sex and age'. Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 33 (4). [DOI] | |
| 2018 | Reynolds, CME; Egan, B; O'Malley, EG; Kennedy, RAK; Sheehan, SR; Turner, MJ (2018) 'A longitudinal, observational study of women who persisted in smoking in successive pregnancies'. Journal of Public Health (United Kingdom), 42 (1). [DOI] | |
| 2020 | Waldman, H.S.; Shepherd, B.D.; Egan, B.; McAllister, M.J. (2020) 'Exogenous ketone salts do not improve cognitive performance during a dual-stress challenge'. International Journal of Sport Nutrition and Exercise Metabolism, 30 . [Link] [DOI] | |
| 2020 | Poff, A.M.; Koutnik, A.P.; Egan, B. (2020) 'Nutritional Ketosis with Ketogenic Diets or Exogenous Ketones: Features, Convergence, and Divergence'. Current Sports Medicine Reports, 19 . [Link] [DOI] | |
| 2019 | Reynolds, CME; Egan, B; O'Malley, EG; McMahon, L; Sheehan, SR; Turner, MJ (2019) 'Longitudinal Study of Maternal BMI in Successive Pregnancies'. Obesity (Silver Spring, Md.), 28 (2). [DOI] | |
| 2020 | Reynolds, CME; Evans, M; Halpenny, C; Hughes, C; Jordan, S; Quinn, A; Hone, M; Egan, B (2020) 'Acute ingestion of beetroot juice does not improve short-duration repeated sprint running performance in male team sport athletes'. Journal Of Sports Sciences, 38 (18). [DOI] | |
| 2020 | Reynolds, C.M.E.; Egan, B.; Daly, N.; McKeating, A.; Sheehan, S.R.; Turner, M.J. (2020) 'The interaction between maternal smoking, illicit drug use and alcohol consumption associated with neonatal outcomes'. Journal of Public Health (United Kingdom), 42 . [Link] [DOI] | |
| 2020 | Reynolds, C.M.E.; Evans, M.; Halpenny, C.; Hughes, C.; Jordan, S.; Quinn, A.; Hone, M.; Egan, B. (2020) 'Acute ingestion of beetroot juice does not improve short-duration repeated sprint running performance in male team sport athletes'. Journal Of Sports Sciences, 38 . [Link] [DOI] | |
| 2022 | Nolan, D.; Lynch, A.E.; Egan, B. (2022) 'Self-Reported Prevalence, Magnitude, and Methods of Rapid Weight Loss in Male and Female Competitive Powerlifters'. Journal of Strength and Conditioning Research, 36 . [Link] [DOI] | |
| 2019 | Krause, M.; Crognale, D.; Cogan, K.; Contarelli, S.; Egan, B.; Newsholme, P.; De Vito, G. (2019) 'The effects of a combined bodyweight-based and elastic bands resistance training, with or without protein supplementation, on muscle mass, signaling and heat shock response in healthy older people'. Experimental Gerontology, 115 . [Link] [DOI] | |
| 2019 | Evans, M.; McSwiney, F.T.; Brady, A.J.; Egan, B. (2019) 'No Benefit of Ingestion of a Ketone Monoester Supplement on 10-km Running Performance'. Medicine and Science in Sports and Exercise, 51 . [Link] [DOI] | |
| 2019 | McMorrow, B.J.; Ditroilo, M.; Egan, B. (2019) 'Effect of heavy resisted sled sprint training during the competitive season on sprint and change-of-direction performance in professional soccer players'. International Journal of Sports Physiology and Performance, 14 . [Link] [DOI] | |
| 2018 | Reynolds, CME; Egan, B; O'Malley, EG; Kennedy, RRA; Sheehan, SR; Turner, MJ (2018) 'Feasibility of recruitment to a behavioural smoking cessation intervention combined with ongoing online support'. European Journal of Public Health, 29 (1). [DOI] | |
| 2019 | Reynolds, C.M.E.; Egan, B.; Kennedy, R.A.; O'Malley, E.; Sheehan, S.R.; Turner, M.J. (2019) 'The implications of high carbon monoxide levels in early pregnancy for neonatal outcomes'. European Journal of Obstetrics and Gynecology and Reproductive Biology, 233 . [Link] [DOI] | |
| 2021 | Massart, J.; Sj?gren, R.J.O.; Egan, B.; Garde, C.; Lindgren, M.; Gu, W.; Ferreira, D.M.S.; Katayama, M.; Ruas, J.L.; Barrès, R.; O’Gorman, D.J.; Zierath, J.R.; Krook, A. (2021) 'Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism'. Nature Communications, 12 . [Link] [DOI] | |
| 2019 | Connor, J.; Egan, B. (2019) 'Prevalence, magnitude and methods of rapid weight loss reported by male mixed martial arts athletes in ireland'. Sports (Basel, Switzerland), 7 . [Link] [DOI] | |
| 2019 | Reynolds, C.M.E.; Egan, B.; McMahon, L.; O'Malley, E.G.; Sheehan, S.R.; Turner, M.J. (2019) 'Maternal obesity trends in a large Irish university hospital'. European Journal of Obstetrics and Gynecology and Reproductive Biology, 238 . [Link] [DOI] | |
| 2018 | Reynolds, CME; Egan, B; O'Malley, EG; McMahon, L; Sheehan, SR; Turner, MJ (2018) 'Fetal growth and maternal alcohol consumption during early pregnancy'. European Journal of Obstetrics and Gynecology and Reproductive Biology, 236 . [DOI] | |
| 2020 | Timmons, J.F.; Griffin, C.; Cogan, K.E.; Matthews, J.; Egan, B. (2020) 'Exercise Maintenance in Older Adults 1 Year After Completion of a Supervised Training Intervention'. Journal of the American Geriatrics Society, 68 . [Link] [DOI] | |
| 2018 | Cogan, KE; Carson, BP; Patel, B; Amigo-Benavent, M; Jakeman, PM; Egan, B (2018) 'Regulation of GLUT4 translocation in an in vitro cell model using postprandial human serum ex vivo'. Experimental Physiology, 104 (6). [DOI] | |
| 2018 | Evans, M.; Patchett, E.; Nally, R.; Kearns, R.; Larney, M.; Egan, B. (2018) 'Effect of acute ingestion of β-hydroxybutyrate salts on the response to graded exercise in trained cyclists'. European Journal Of Sport Science, 18 . [Link] [DOI] | |
| 2018 | Evans M, Egan B (2018) 'Intermittent Running and Cognitive Performance after Ketone Ester Ingestion'. Medicine and Science in Sports and Exercise, . | |
| 2018 | Timmons, J.F.; Minnock, D.; Hone, M.; Cogan, K.E.; Murphy, J.C.; Egan, B. (2018) 'Comparison of time-matched aerobic, resistance, or concurrent exercise training in older adults'. Scandinavian Journal of Medicine and Science in Sports, 28 . [Link] [DOI] | |
| 2018 | Cogan KE, Evans M, Iuliano E, Melvin A, Susta D, Neff K, De Vito G, Egan B (2018) 'Co-ingestion of protein or a protein hydrolysate with carbohydrate enhances anabolic signaling, but not glycogen resynthesis, following recovery from prolonged aerobic exercise in trained cyclists'. European Journal of Applied Physiology, 118 (2):349-359. [DOI] | |
| 2018 | Reynolds, CME; Egan, B; Kennedy, RA; O'Malley, EG; Sheehan, SR; Turner, MJ (2018) 'A prospective, observational study investigating the use of carbon monoxide screening to identify maternal smoking in a large university hospital in Ireland'. BMJ Open, 8 (7). [DOI] | |
| 2018 | Kelly, D.T.; Tobin, C.; Egan, B.; McCarren, A.; O'Connor, P.L.; Mccaffrey, N.; Moyna, N.M. (2018) 'Comparison of sprint interval and endurance training in team sport athletes'. Journal of Strength and Conditioning Research, 32 . [Link] [DOI] | |
| 2018 | Moran C, Scotto di Palumbo A, Bramham J, Moran A, Rooney B, De Vito G, Egan B (2018) 'Effects of a Six-Month Multi-Ingredient Nutrition Supplement Intervention of Omega-3 Polyunsaturated Fatty Acids, Vitamin D, Resveratrol, and Whey Protein on Cognitive Function in Older Adults: A Randomised, Double-Blind, Controlled Trial'. 5 (3). | |
| 2018 | Reynolds CME, Egan B, Kennedy RA, O'Malley EG, Sheehan SR, Turner MJ (2018) 'A prospective, observational study investigating the use of carbon monoxide screening to identify maternal smoking in a large university hospital in Ireland'. BMJ Open, 8 (7). | |
| 2017 | Evans, M; Tierney, P; Gray, N; Hawe, G; Macken, M; Egan, B (2017) 'Acute Ingestion of Caffeinated Chewing Gum Improves Repeated Sprint Performance of Team Sport Athletes With Low Habitual Caffeine Consumption'. International Journal of Sport Nutrition and Exercise Metabolism, 28 (3). [DOI] | |
| 2018 | Cogan KE, Egan B (2018) 'Effects of acute ingestion of whey protein with or without prior aerobic exercise on postprandial glycemia in type 2 diabetics'. European Journal of Applied Physiology, 118 (9):1959-1968. | |
| 2017 | Petrakos, G; Tynan, NC; Vallely-Farrell, AM; Kiely, C; Boudhar, A; Egan, B (2017) 'Reliability of the Maximal Resisted Sprint Load Test and Relationships With Performance Measures and Anthropometric Profile in Female Field Sport Athletes'. Journal of Strength and Conditioning Research, 33 (6). [DOI] | |
| 2017 | Reynolds, C.M.E.; Egan, B.; Cawley, S.; Kennedy, R.; Sheehan, S.R.; Turner, M.J. (2017) 'A national audit of smoking cessation services in irish maternity units'. Irish Medical Journal, 110 . [Link] | |
| 2017 | Reynolds CME, Egan B, McKeating A, Daly N, Sheehan SR, Turner MJ (2017) 'Five year trends in maternal smoking behaviour reported at the first prenatal appointment'. Irish Journal of Medical Science, 186 (4):971-979. [DOI] | |
| 2017 | Massart J, Sj?gren RJO, Lundell LS, Mudry JM, Franck N, O'Gorman DJ, Egan B, Zierath JR, Krook A (2017) 'Altered miR-29 Expression in Type 2 Diabetes Influences Glucose and Lipid Metabolism in Skeletal Muscle'. Diabetes, 66 (7):1807-1818. [DOI] | |
| 2016 | Petrakos G, Morin JB, Egan B (2016) 'Resisted Sled Sprint Training to Improve Sprint Performance: A Systematic Review'. Sports medicine (Auckland, N.Z.), 46 (3):381-400. [DOI] | |
| 2016 | Riedl I, Osler ME, Bj?rnholm M, Egan B, Nader GA, Chibalin AV, Zierath JR (2016) 'AMPKγ3 is dispensable for skeletal muscle hypertrophy induced by functional overload'. American Journal of Physiology- Endochrinology and Metabolism, 310 (6):E461-E472. [DOI] | |
| 2016 | Egan B, Ashley DT, Kennedy E, O’Connor PL, O’Gorman DJ (2016) 'Higher rate of fat oxidation during rowing compared with cycling ergometer exercise across a range of exercise intensities'. Scandinavian Journal of Medicine and Science in Sports, 26 (6):630-637. [DOI] | |
| 2016 | Egan B, D'Agostino DP (2016) 'Fueling Performance: Ketones Enter the Mix'. Cell Metabolism, 24 (3):373-375. [DOI] | |
| 2016 | Egan B (2016) 'Protein intake for athletes and active adults: Current concepts and controversies'. Nutrition Bulletin, 41 (3):202-213. [DOI] | |
| 2016 | Egan B, Hawley JA, Zierath JR (2016) 'SnapShot: Exercise Metabolism'. Cell Metabolism, 24 (2):342-342. [DOI] | |
| 2015 | Sjogren RJ, Egan B, Katayama M, Zierath JR, Krook A (2015) 'Temporal analysis of reciprocal miRNA-mRNA expression patterns predicts regulatory networks during differentiation in human skeletal muscle cells'. Physiological Genomics, 47 (3):45-57. [DOI] | |
| 2015 | Boon H, Sjogren RJ, Massart J, Egan B, Kostovski E, Iversen PO, Hjeltnes N, Chibalin AV, Widegren U, Zierath JR (2015) 'MicroRNA-208b progressively declines after spinal cord injury in humans and is inversely related to myostatin expression'. Physiological Reports, 3 (11). [DOI] | |
| 2015 | Katayama M, Sjogren RJ, Egan B, Krook A (2015) 'miRNA let-7 expression is regulated by glucose and TNF-$\alpha$ by a remote upstream promoter'. Biochemical Journal, 472 (2):147-156. [DOI] | |
| 2014 | Krause M, Keane K, Rodrigues-Krause J, Crognale D, Egan B, De Vito G, Murphy C, Newsholme P (2014) 'Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistance in vivo and cause pancreatic $\beta$-cell dysfunction and death in vitro'. Clinical Science, 126 (10):739-752. [DOI] | |
| 2013 | Egan B, Zierath JR (2013) 'Exercise metabolism and the molecular regulation of skeletal muscle adaptation'. Cell Metabolism, 17 (2):162-184. [DOI] | |
| 2013 | Jiang LQ, Franck N, Egan B, Sjogren RJ, Katayama M, Duque-Guimaraes D, Arner P, Zierath JR, Krook A (2013) 'Autocrine role of interleukin-13 on skeletal muscle glucose metabolism in type 2 diabetic patients involves microRNA let-7'. American Journal of Physiology- Endochrinology and Metabolism, 305 (11):E1359-E1366. [DOI] | |
| 2013 | Egan B, O'Connor PL, Zierath JR, O'Gorman DJ (2013) 'Time course analysis reveals gene-specific transcript and protein kinetics of adaptation to short-term aerobic exercise training in human skeletal muscle'. PLoS ONE, 8 (9). [DOI] | |
| 2012 | Barrès R, Yan J, Egan B, Treebak JT, Rasmussen M, Fritz T, Caidahl K, Krook A, O'Gorman DJ, Zierath JR (2012) 'Acute exercise remodels promoter methylation in human skeletal muscle'. Cell Metabolism, 15 (3):405-411. [DOI] | |
| 2012 | Iglesias-Gutierrez E, Egan B, Diaz-Martinez AE, Penalvo JL, Gonzalez-Medina A, Martinez-Camblor P, O'Gorman DJ, Ubeda N (2012) 'Transient increase in homocysteine but not hyperhomocysteinemia during acute exercise at different intensities in sedentary individuals'. PLoS ONE, 7 (12). [DOI] | |
| 2011 | Egan, B.; Dowling, P.; O'Connor, P.L.; Henry, M.; Meleady, P.; Zierath, J.R.; O'Gorman, D.J. (2011) '2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training'. Proteomics, 11 . [Link] [DOI] | |
| 2010 | Egan B, Carson BP, Garcia-Roves PM, Chibalin AV, Sarsfield FM, Barron N, McCaffrey N, Moyna NM, Zierath JR, O'Gorman DJ (2010) 'Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle'. JOURNAL OF PHYSIOLOGY (LONDON), 588 (10):1779-1790. [DOI] | |
| 2009 | Egan B, Zierath JR (2009) 'Hunting for the SNARK in metabolic disease'. American Journal of Physiology- Endochrinology and Metabolism, 296 (5):E969-E972. [DOI] | |
| 2023 | Nolan, D.; Curran, O.; Brady, A.J.; Egan, B. (2023) 'Physical Match Demands of International Women’s Rugby Union: A Three-Year Longitudinal Analysis of a Team Competing in The Women’s Six Nations Championship'. Journal of functional morphology and kinesiology, 8 . [Link] [DOI] | |
| 2022 | Connor, J; Germaine, M; Gibson, C; Clarke, P; Egan, B (2022) 'Effect of rapid weight loss incorporating hot salt water immersion on changes in body mass, blood markers, and indices of performance in male mixed martial arts athletes'. European Journal of Applied Physiology, 122 (10). [DOI] | |
| 2023 | Monedero, J.; Duff, C.; Egan, B. (2023) 'Dietary Intakes and the Risk of Low Energy Availability in Male and Female Advanced and Elite Rock Climbers'. Journal of Strength and Conditioning Research, 37 . [Link] [DOI] | |
| 2022 | Monahan, M; Petrakos, G; Egan, B (2022) 'Physiological and Perceptual Responses to a Single Session of Resisted Sled Sprint Training at Light or Heavy Sled Loads'. Journal of Strength and Conditioning Research, 36 (10). [DOI] | |
| 2022 | Monahan, M; Egan, B (2022) 'The Priming Effect of a Heavy or Very Heavy Resisted Sled Sprint-Based Conditioning Activity on Subsequent Unresisted Sprint Performance in Team Field Sport Athletes'. Journal of Strength and Conditioning Research, 37 (1). [DOI] | |
| 2023 | Darragh, Ian A. J.; Aird, Tom P. P.; O'Sullivan, Aifric; Egan, Brendan; Carson, Brian P. P. (2023) 'The resting serum metabolome in response to short-term sprint interval training'. European Journal of Applied Physiology, 123 (4). [DOI] | |
| 2022 | Darragh, IAJ; O'Driscoll, L; Egan, B (2022) 'Within-Subject Variability and the Influence of Exercise Training History on the Resting Plasma Metabolome in Men'. International Journal of Sport Nutrition and Exercise Metabolism, 33 (3). [DOI] | |
| 2022 | Timmons, J.F.; Hone, M.; Duffy, O.; Egan, B. (2022) 'When Matched for Relative Leg Strength at Baseline, Male and Female Older Adults Respond Similarly to Concurrent Aerobic and Resistance Exercise Training'. Journal of Strength and Conditioning Research, 36 . [Link] [DOI] | |
| 2018 | Egan, B (2018) 'The glucose-lowering effects of exogenous ketones: is there therapeutic potential?'. The Journal of physiology, 596 (8). [DOI] | |
| 2024 | Faria, V.S.; Egan, B. (2024) 'Effects of 3?days of citrulline malate supplementation on short-duration repeated sprint running performance in male team sport athletes'. European Journal Of Sport Science, 24 . [Link] [DOI] | |
| 2024 | Brady, A.J.; Egan, B. (2024) 'Acute Ingestion of a Ketone Monoester without Co-ingestion of Carbohydrate Improves Running Economy in Male Endurance Runners'. Medicine and Science in Sports and Exercise, 56 . [Link] [DOI] | |
| 2024 | Waldman, H.S.; O’Neal, E.K.; Barker, G.A.; Witt, C.R.; Lara, D.A.; Huber, A.K.; Forsythe, V.N.; Koutnik, A.P.; D’Agostino, D.P.; Staiano, W.; Egan, B. (2024) 'A Ketone Monoester with Carbohydrate Improves Cognitive Measures Postexercise, but Not Performance in Trained Females'. Medicine and Science in Sports and Exercise, 56 . [Link] [DOI] | |
| 2023 | Darragh, Ian A. J.; McNamee, Niamh; Daly, Roisin; Pacheco, Sarai Martinez; O'Driscoll, Lorraine; Egan, Brendan (2023) 'The separation and identification of circulating small extracellular vesicles from endurance-trained, strength-trained and recreationally active men'. Journal of Physiology-London, 601 (22). [DOI] | |
| 2023 | Darragh, I.A.J.; Martinez-Pacheco, S.; O'Driscoll, L.; Egan, B. (2023) 'Functional assays reflective of cancer hallmarks in BT-549 cells are not impacted by media supplemented with exercise-trained plasma'. Experimental Physiology, . [Link] [DOI] | |
| 2023 | Nolan, D.; Horgan, P.; MacNamara, A.; Egan, B. (2023) '‘There’s a perfect way to do things, and there’s a real way to do things’: Attitudes, beliefs and practices of strength and conditioning coaches in elite international women's rugby union'. International Journal of Sports Science and Coaching, 18 . [Link] [DOI] | |
| 2023 | Waldman, Hunter S.; O'Neal, Eric K.; Barker, Gaven A.; Witt, Craig R.; Lara, David A.; Huber, Anna K.; Forsythe, Valerie N.; Koutnik, Andrew P.; D'Agostino, Dominic P.; Staiano, Walter; Egan, Brendan (2023) 'No Benefit of Ingesting a Low-Dose Ketone Monoester Supplement on Markers of Cognitive Performance in Females'. Journal of Cognitive Enhancement, 7 (3-4). [DOI] | |
| 2023 | Brady, AJ; Roantree, M; Egan, B (2023) 'Test-Retest Reliability of Running Economy and Metabolic and Cardiorespiratory Parameters During a Multistage Incremental Treadmill Test in Male Middle- and Long-Distance Runners'. International Journal of Sport Nutrition and Exercise Metabolism, . [DOI] | |
| 2023 | Murphy, C.H.; McCarthy, S.N.; McMorrow, A.M.; Egan, B.; McGowan, M.J.; Rafferty, S.; Corish, C.A.; Roche, H.M. (2023) 'Prevalence and determinants of sarcopenia in community-dwelling older adults in Ireland'. Aging clinical and experimental research, 35 . [Link] [DOI] | |
| 2022 | Timmons, James F.; Hone, Michelle; Duffy, Orlaith; Egan, Brendan (2022) 'When Matched for Relative Leg Strength at Baseline, Male and Female Older Adults Respond Similarly to Concurrent Aerobic and Resistance Exercise Training'. Journal of Strength and Conditioning Research, 36 (10). |
Publications letters
Other Publication
| Year | Publication | |
|---|---|---|
| 2020 | Davey, D; Malone, S; Egan, B (2020) Case Study: Transition to a Vegan Diet in an Elite Male Gaelic Football Player. [DOI] | |
| 2020 | Connor, J; Shelley, A; Egan, B (2020) Comparison of hot water immersion at 37.8°C with or without salt for rapid weight loss in mixed martial arts athletes. [DOI] | |
| 2019 | Koutnik, A.P.; D'Agostino, D.P.; Egan, B. (2019) Anticatabolic Effects of Ketone Bodies in Skeletal Muscle. [Link] [DOI] | |
| 2017 | Hone, M; Kent, RM; Scotto di Palumbo, A; Bleiel, SB; De Vito, G; Egan, B (2017) Plasma Creatine Kinetics After Ingestion of Microencapsulated Creatine Monohydrate with Enhanced Stability in Aqueous Solutions. [DOI] | |
| 2017 | Evans, M.; Cogan, K.E.; Egan, B. (2017) Metabolism of ketone bodies during exercise and training: physiological basis for exogenous supplementation. [Link] [DOI] | |
| 2022 | Evans, M.; McClure, T.S.; Koutnik, A.P.; Egan, B. (2022) Exogenous Ketone Supplements in Athletic Contexts: Past, Present, and Future. [Link] [DOI] | |
| 2023 | Egan, B.; Sharples, A.P. (2023) MOLECULAR RESPONSES TO ACUTE EXERCISE AND THEIR RELEVANCE FOR ADAPTATIONS IN SKELETAL MUSCLE TO EXERCISE TRAINING. [Link] [DOI] | |
| 2019 | Reynolds, CME; O'Malley, EG; Egan, B; Sheehan, SR; Turner, MJ (2019) Maternal Weight Trajectories in Successive Pregnancies and Their Association With Gestational Diabetes Mellitus. [DOI] | |
| 2021 | Darragh, I.A.J.; O’Driscoll, L.; Egan, B. (2021) Exercise Training and Circulating Small Extracellular Vesicles: Appraisal of Methodological Approaches and Current Knowledge. [Link] [DOI] | |
| 2024 | Ashcroft, S.P.; Stocks, B.; Egan, B.; Zierath, J.R. (2024) Exercise induces tissue-specific adaptations to enhance cardiometabolic health. [Link] [DOI] | |
| 2024 | Darragh, I.A.J.; Egan, B. (2024) Considerations for exerkine research focusing on the response to exercise training. [Link] [DOI] |
Review Articles
| Year | Publication | |
|---|---|---|
| 2024 | Nolan, David; Mcnulty, Kelly L.; Manninen, Mika; Egan, Brendan (2024) The Effect of Hormonal Contraceptive Use on Skeletal Muscle Hypertrophy, Power and Strength Adaptations to Resistance Exercise Training: A Systematic Review and Multilevel Meta-analysis. REV [DOI] |
Certain data included herein are derived from the ? Web of Science (2024) of Clarivate. All rights reserved.
Professional Associations
Research Interests
Skeletal muscle metabolism, function, and adaptation in exercise, health and disease
My research revolves around function and adaptation in skeletal muscle, and the central role of skeletal muscle in whole body metabolism and performance. As the largest organ in the body, skeletal muscle typically accounts for ~40% of total body mass, and is a major player in energy balance at rest by contributing ~30% of the resting metabolic rate in adults. Skeletal muscle has a critical role in glycemic control and metabolic homeostasis by virtue of being the predominant site of glucose disposal under insulin-stimulated conditions. Importantly, insulin resistance at the level of skeletal muscle is the primary defect in type 2 diabetes mellitus (T2DM), and linked to myriad of lifestyle-related chronic disease including where declines in skeletal muscle function and size are a major threat to healthy ageing. My research therefore investigates skeletal muscle function and adaptation across the life course with special interest in the synergy between nutrition and exercise interventions in populations ranging from athletes to older adults.
Applied sports science and nutrition
My interest in applied sports science centres on nutrition and exercise training interventions to optimise athletic performance, and in particular in sports with high intensity and/or repeated sprint/maximal effort demands. Current projects include resisted sled sprinting, weight cutting in combat sports, and menstrual cycle and hormonal contraceptive use, as well as nutrition supplementation and performance such including exogenous ketones, beetroot juice and caffeinated chewing gum.